How to Get the Eyes of Despair Sasuke Familiar Fast Anime Vanguards Guide
If you’re trying to unlock the Eyes of Despair Vanguard Sasuke Familiar fast in Anime Vanguards, the grinding process may look annoying at first. The good news is there’s a method that lets you rush through the requirements much faster, especially if you don’t want to spend hours clearing stages repeatedly.
This guide explains what you need before starting, how to build the right team setup, and the farming route that will help you complete the familiar requirements efficiently. Also check out our Anime Vanguards Codes for more rewards!
Requirements Before You Start

Before jumping into the farming stage, there’s one important thing:
- You must have the evolved version of Sasuke.
If you only have the base unit, evolve him first. You’ll need Snake Scales to evolve Sasuke, so craft or synthesize them until you have enough. Once evolved, feed and fuse units until he reaches a usable level. Even around level 60 works fine, especially if you have a farm unit to support him.
A good trait is helpful, but not required. If you have rerolls available, feel free to try for a stronger trade. Otherwise, continue without worrying too much.
Best Team Setup

To make this method work smoothly, use this lineup:
- Main Unit: Evolved Sasuke (lead)
- Three Un-evolved Exclusive Units
- Two Farm Units (Speed Cart or Takarada recommended)
If you don’t own exclusive mythics, don’t worry. Other units will still work, but this setup speeds things up.
Farming Method for Fast Progress

Once your team is ready, follow these steps:
- Head to Odyssey Limitless Mode.
- Load in and place Sasuke once the match starts.
- Continue until you reach Wave 15.
- Upgrade Sasuke until he reaches his final attack stage.
Target priority matters because Sasuke isn’t the strongest early on. Use this targeting setup:
- One Sasuke on Last
- One on Closest
- One on First
- If possible, set one to Boss Focus
With a farm unit covering cost and upgrades, clearing waves becomes much easier. On average, this method takes around a minute per run, depending on the map and boss spawns. Frieza is usually the longest boss encounter, but it won’t slow you down too much.
Why This Method Works
The familiar progression system counts kills and completions, and Limitless Mode gives you both quickly. Since objectives reset daily, this approach helps maximize every reset without wasting time. Even if you miss a reset day, repeating this method still speeds up progress compared to running random stages.
Unlocking the Eyes of Despair Sasuke Familiar may seem like a grind, but with the right setup and farming method, you can finish it much faster. Once you get the familiar, the payoff is worth it since Sasuke already has a solid stun ability and strong evolution potential.
If you’re planning to continue upgrading him, keep resources ready because future forms and shiny versions may require even more materials. That’s the full method to get Sasuke’s Vanguard familiar fast in Anime Vanguards. Use this routine daily, and you’ll unlock him much quicker than most players.
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