Mutations play a big role in Run for Brainrots. If you want to increase your earnings and boost your sale value, hunting mutated brainrots should be your main focus. Each mutation comes with a different multiplier and visual change, making them easy to spot once you know what to look for. There are four main mutations available in the game. Some appear naturally, while others are tied to limited-time events. Below is a full breakdown of every mutation, its multiplier, appearance, and how you can obtain it.
All Run for Brainrots Mutation Guide
1. Gold Mutation
- Multiplier: 1.75x earning rate and sale value
- Appearance: Yellow body with the word “Golden” above its head
Gold is one of the most common mutations in the game. You can find Golden brainrots spawning naturally in most areas. While the chance is not guaranteed, they appear regularly during normal gameplay. If you want a better opportunity, wait for the Golden Rush event. During this event, the spawn rate for Gold brainrots increases, making it easier to farm them.
2. Diamond Mutation
- Multiplier: 2x earning rate and sale value
- Appearance: Blue body with the word “Diamond” above its head
Diamond mutations offer a stronger multiplier compared to Gold. Like Gold, Diamond brainrots can spawn naturally, though they are slightly less common. Your best chance to farm them is during the Diamond Dominion event, where their spawn rate increases significantly.
3. Ruby Mutation
- Multiplier: 2.5x earning rate and sale value
- Appearance: Bright red body with the word “Ruby” above its head
Ruby mutations are rarer than Gold and Diamond but still possible to find outside of events. They provide a noticeable boost to profits, making them highly desirable for farming. During the Ruby Rampage event, Ruby brainrots spawn more frequently. If you’re targeting high-value sales, this is the best time to grind.
4. Neon Mutation
- Multiplier: 5x earning rate and sale value
- Appearance: Labeled “Neon” above the head
Neon is the rarest and most valuable mutation in Run for Brainrots. Unlike the others, Neon brainrots do not spawn naturally at all. They are only available during the Neon Night event, and even then, their spawn rate is extremely low. To improve your chances, search in high-rarity areas where stronger brainrots usually appear.
Which Mutation Is Best?
If you’re farming casually, Gold and Diamond are reliable options since they spawn often. Ruby is a solid middle ground with better multipliers and reasonable availability during events. However, Neon is the ultimate target. With a 5x multiplier, it offers the highest earning potential in the game.
The challenge is actually finding one. If your goal is maximum profit in Run for Brainrots, keep track of active events and prioritize farming during boosted spawn periods. Timing matters just as much as location when hunting for the best mutations.